SARS-CoV-2 3CLpro probe-1

SARS-CoV-2 3CLpro probe-1 (Compound probe 3) is a selective and activity-based probe for the SARS-CoV-2 3CL protease. SARS-CoV-2 3CLpro probe-1 can detect endogenously expressed 3CLpro in SARS-CoV-2-infected cells[1].

Product Specifications

UNSPSC

12171500

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/sars-cov-2-3clpro-probe-1.html

Solubility

10 mM in DMSO

Smiles

O=C(N[C@@H](CC(C)C)C(N[C@@H](C[C@@H]1CCNC1=O)C(COC(C2=C(Cl)C=CC=C2Cl)=O)=O)=O)C3=CC(C(OCC#C)=CC=C4)=C4N3

Molecular Formula

C33H34Cl2N4O7

Molecular Weight

669.55

References & Citations

[1]Yamauchi Y, et al. Detection of Active SARS-CoV-2 3CL Protease in Infected Cells Using Activity-Based Probes with a 2,6-Dichlorobenzoyloxymethyl Ketone Reactive Warhead. ACS Chem Biol. 2024;19 (5) :1028-1034.