SAG-524
SAG-524 is a potent oral small molecule HBV viral replication inhibitor. SAG-524 decreased HBV-DNA and HbsAg levels in supernatant of HepG2.2.15 cells, IC50 0.92 and 1.4 nM, respectively[1].
Product Specifications
CAS Number
[2246696-89-7]
UNSPSC
12352005
Target
HBV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/sag-524.html
Purity
98.50
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
COCCN1CCN(CC1)C2=NC3=CC=C(C=C3S2)N4C=C(C(C=C4C5=CC(Cl)=C(C=C5)N6CCCC6)=O)C(O)=O
Molecular Formula
C30H32ClN5O4S
Molecular Weight
594.12
References & Citations
[1]Watanabe T, et al. A novel, small anti-HBV compound reduces HBsAg and HBV-DNA by destabilizing HBV-RNA. J Gastroenterol. 2024 Feb 5.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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