Amycolatopsin A
Amycolatopsin A is a 20-membered macrolide, that can be isolated from a strain of the rare actinomycete Amycolatopsis sp. MST‐108494. Amycolatopsin A shows antimycobacterial activity against Mycobacterium bovis (BCG) and M. tuberculosis (H37Rv) with IC50 values of 0.4 µM and 4.4 µM, respectively[1].
Product Specifications
CAS Number
2209112-96-7
UNSPSC
12352005
Target
Bacterial
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/amycolatopsin-a.html
Solubility
10 mM in DMSO
Smiles
C[C@]1([C@H](O[C@](O)([C@@H]([C@H]1O)OC)[C@@H](C2([H])CC(C(/C=C(/C=C(/C=C(C(C(/C=C(/C=C(\C=C(C(O2)=O)/C)OC)CO)C)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)C)OC)O)O)/C)C)C)O)OC)C)CCCOC)O[C@H]4C[C@@H]([C@@H]([C@H](O4)C)O[C@H]5C[C@@](O)([C@@H]([C@H](O5)C)O)C)O
Molecular Formula
C60H98O23
Molecular Weight
1187.41
References & Citations
[1]Al-Fadhli AA, et al. Macrolides from rare actinomycetes: Structures and bioactivities. Int J Antimicrob Agents. 2022 Feb;59 (2) :106523.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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