Thromboxane B3

Thromboxane B3 is a prostaglandin analog derived from arachidonic acid (AA) in the cyclooxygenase (COX) metabolic pathway. Thromboxane B3 is generated from arachidonic acid (AA) in platelets and vascular endothelial cells through the catalysis of cyclooxygenase (COX) and thromboxane synthase (TXS) . Thromboxane B3 has been reported to be formed by human platelets upon ingestion of eicosapentaenoic acid (C20: 5ω3) [1][2].

Product Specifications

CAS Number

[71953-80-5]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

COX; Endogenous Metabolite

Type

Reference compound

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/thromboxane-b3.html

Concentration

271.40 μM * 1 mL in Methyl acetate

Purity

95.0

Solubility

10 mM in DMSO

Smiles

O=C(O)CCC/C=C\C[C@@H]1[C@@H](/C=C/[C@@H](O)C/C=C\CC)OC(O)C[C@@H]1O

Molecular Formula

C20H32O6

Molecular Weight

368.46

Precautions

H302, H315, H319, H335

References & Citations

[1]Fischer S, et al. Thromboxane A3 (TXA3) is formed in human platelets after dietary eicosapentaenoic acid (C20: 5ω3) [J]. Biochemical and biophysical research communications, 1983, 116 (3) : 1091-1099.