(S) -Veliflapon
(S) -Veliflapon ((S) -BAY X 1005) is an orally active inhibitor of leukotriene biosynthesis and 5-lipoxygenase activating protein (FLAP) . (S) -Veliflapon inhibits the formation of leukotriene B4 (LTB4) in rat, mouse and human leukocytes with IC50 values of 0.026 µM, 0.039 µM and 0.22 µM respectively. (S) -Veliflapon showes enantioselectivity in human whole blood[1][2][3].
Product Specifications
CAS Number
128253-32-7
Product Name Alternative
(S) -BAY X 1005; (S) -DG-031
UNSPSC
12352005
Target
FLAP; Leukotriene Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/s-veliflapon.html
Purity
99.44
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(O)[C@@H](C1CCCC1)C(C=C2)=CC=C2OCC3=NC4=CC=CC=C4C=C3
Molecular Formula
C23H23NO3
Molecular Weight
361.43
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
P21 / WAF1 (WA-1), CF740 conjugate, 0.1mg/mL
MUC18 / Mucin 18 / CD146 (OJ79c), CF594 conjugate, 0.1mg/mL
P27 / KIP1 (SX53G8), CF568 conjugate, 0.1mg/mL
