Stigmasta-4,22-dien-3-one

Stigmasta-4,22-dien-3-one is an antitubercular agent. Stigmasta-4,22-dien-3-one shows cytotoxicity against human HT1080 tumoral cell line with an IC50 of 0.3 mM[1][2].

Product Specifications

CAS Number

[20817-72-5]

UNSPSC

12352211

Target

Bacterial

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/stigmasta-4-22-dien-3-one.html

Purity

98.82

Solubility

Ethanol : 25 mg/mL (ultrasonic)

Smiles

C[C@@]12[C@](CC[C@]2([H])[C@H](C)/C=C/[C@@H](CC)C(C)C)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4(C(CC3)=CC(CC4)=O)C

Molecular Formula

C29H46O

Molecular Weight

410.67

References & Citations

[1]Saludes JP, et al. Antitubercular constituents from the hexane fraction of Morinda citrifolia Linn. (Rubiaceae) . Phytother Res. 2002 Nov;16 (7) :683-5. |[2]Sandjo L P, et al. Cytotoxic effect of some pentacyclic triterpenes and hemisynthetic derivatives of stigmasterol. Chemistry of Natural Compounds, 2011, 47 (5) : 731-734.