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15-epi-PGE1

15-epi-PGE1 (15R-Prostaglandin E1; 15-Epiprostaglandin E1) is a stereoisomer of PGE1 but with less biological activity[2]. 15-epi-PGE1 is a non-competitive inhibitor for human placental 15-Hydroxyprostaglandin dehydrogenase (15-PGDH) with an IC50 of 170 μM[1].

Product Specifications

CAS Number

20897-91-0

Product Name Alternative

15 (R) -Prostaglandin E1; 15-Epiprostaglandin E1

UNSPSC

12352211

Hazard Statement

H225-H319-H336

Target

15-PGDH

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/15-epi-pge1.html

Solubility

10 mM in DMSO

Smiles

OC(CCCCCC[C@@H]1[C@H]([C@@H](CC1=O)O)/C=C/[C@H](O)CCCCC)=O

Molecular Formula

C20H34O5

Molecular Weight

354.48

Precautions

P210-P233-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P370+P378-P403+P233-P403+P235-P405-P501

References & Citations

[1]Jarabak J, et al., Kinetic studies on a 15-hydroxyprostaglandin dehydrogenase from human placenta. Arch Biochem Biophys. 1976 Nov;177 (1) :245-54. |[2]MURAKAMI A, et al., Conformational analysis of prostaglandins. II. Most probable conformation of prostaglandin A, B, E, and F. Chemical and Pharmaceutical Bulletin. 1977 25 (1) :2870-2874

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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