Recombinant EGFR Protein

<strong>Recombinant EGFR Protein</strong>_x000D_ <strong>Catalog number:</strong> B2017516_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> ~91.002 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -80°C_x000D_ <strong>Keywords:</strong> ERBB, HER1, mENA, ERBB1, PIG61, NISBD2_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Sha H, Li R, Bian X, Liu Q, Xie C, Xin X, Kong W, Qian X, Jiang X, Hu W, Liu B. A tumor-penetrating recombinant protein anti-EGFR-iRGD enhance efficacy of paclitaxel in 3D multicellular spheroids and gastric cancer in vivo Eur J Pharm Sci. 2015 Sep 18;77:60-72._x000D_ 2: Kozer N, Barua D, Henderson C, Nice EC, Burgess AW, Hlavacek WS, Clayton AH. Recruitment of the adaptor protein Grb2 to EGFR tetramers Biochemistry. 2014 Apr 29;53(16):2594-604._x000D_ 3: Cicek E, Circir A, Oyken M, Akbulut Caliskan O, Dioken DN, Guntekin Ergun S, Cetin-Atalay R, Sapmaz A, Ovaa H, Sahin O, Erson-Bensan AE. EGF-SNX3-EGFR axis drives tumor progression and metastasis in triple-negative breast cancers Oncogene. 2022 Jan;41(2):220-232._x000D_ 4: Shao Y, Zhong D. [Gene Fusions as Acquired Resistance Mechanisms of EGFR-TKI] Zhongguo Fei Ai Za Zhi. 2020 May 20;23(5):381-387._x000D_ 5: Ai Z, Wang J, Wang Y, Lu L, Tong J, Teng Y. Overexpressed epidermal growth factor receptor (EGFR)-induced progestin insensitivity in human endometrial carcinoma cells by the EGFR/mitogen-activated protein kinase signaling pathway Cancer. 2010 Aug 1;116(15):3603-13._x000D_ 6: Koustas E, Karamouzis MV, Mihailidou C, Schizas D, Papavassiliou AG. Co-targeting of EGFR and autophagy signaling is an emerging treatment strategy in metastatic colorectal cancer Cancer Lett. 2017 Jun 28;396:94-102._x000D_ 7: Hadac EM, Peng KW, Nakamura T, Russell SJ. Reengineering paramyxovirus tropism Virology. 2004 Nov 24;329(2):217-25._x000D_ 8: Bublil EM, Pines G, Patel G, Fruhwirth G, Ng T, Yarden Y. Kinase-mediated quasi-dimers of EGFR FASEB J. 2010 Dec;24(12):4744-55._x000D_ 9: Lyakhov I, Zielinski R, Kuban M, Kramer-Marek G, Fisher R, Chertov O, Bindu L, Capala J. HER2- and EGFR-specific affiprobes: novel recombinant optical probes for cell imaging Chembiochem. 2010 Feb 15;11(3):345-50._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/33976119">10: Bahl S, Ling H, Acharige NPN, Santos-Barriopedro I, Pflum MKH, Seto E. EGFR phosphorylates HDAC1 to regulate its expression and anti-apoptotic function Cell Death Dis. 2021 May 11;12(5):469. </a>_x000D_ _x000D_ <strong>Products Related to Recombinant EGFR Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>