Eosinophil Peroxidase (Native Human)

<strong>Eosinophil Peroxidase (Native Human)</strong>_x000D_ <strong>Catalog number:</strong> B2016847_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 1.0 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 70.5 kDa_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -80°C_x000D_ <strong>Keywords:</strong> Eosinophil peroxidase, EPX_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Romano M, Baralle FE, Patriarca P. Expression and characterization of recombinant human eosinophil peroxidase. Impact of the R286H substitution on the biosynthesis and activity of the enzyme Eur J Biochem. 2000 Jun;267(12):3704-11._x000D_ 2: Esposito I, Kontra I, Giacomassi C, Manou-Stathopoulou S, Brown J, Stratton R, Verykokou G, Buccafusca R, Stevens M, Nissim A, Lewis MJ, Pfeffer PE. Identification of autoantigens and their potential post-translational modification in EGPA and severe eosinophilic asthma Front Immunol. 2023 Jun 2;14:1164941._x000D_ 3: Olsen RL, Little C. Purification and some properties of myeloperoxidase and eosinophil peroxidase from human blood Biochem J. 1983 Mar 1;209(3):781-7._x000D_ 4: Arnhold J, Furtmüller PG, Regelsberger G, Obinger C. Redox properties of the couple compound I/native enzyme of myeloperoxidase and eosinophil peroxidase Eur J Biochem. 2001 Oct;268(19):5142-8._x000D_ 5: Ciaccio C, Gambacurta A, De Sanctis G, Spagnolo D, Sakarikou C, Petrella G, Coletta M. rhEPO (recombinant human eosinophil peroxidase): expression in Pichia pastoris and biochemical characterization Biochem J. 2006 Apr 15;395(2):295-301._x000D_ 6: Furtmüller PG, Jantschko W, Regelsberger G, Obinger C. Spectral and kinetic studies on eosinophil peroxidase compounds I and II and their reaction with ascorbate and tyrosine Biochim Biophys Acta. 2001 Jul 9;1548(1):121-8._x000D_ 7: Chu DK, Jimenez-Saiz R, Verschoor CP, Walker TD, Goncharova S, Llop-Guevara A, Shen P, Gordon ME, Barra NG, Bassett JD, Kong J, Fattouh R, McCoy KD, Bowdish DM, Erjefält JS, Pabst O, Humbles AA, Kolbeck R, Waserman S, Jordana M. Indigenous enteric eosinophils control DCs to initiate a primary Th2 immune response in vivo J Exp Med. 2014 Jul 28;211(8):1657-72._x000D_ 8: Lotfi R, Herzog GI, DeMarco RA, Beer-Stolz D, Lee JJ, Rubartelli A, Schrezenmeier H, Lotze MT. Eosinophils oxidize damage-associated molecular pattern molecules derived from stressed cells J Immunol. 2009 Oct 15;183(8):5023-31._x000D_ 9: Furtmüller PG, Burner U, Regelsberger G, Obinger C. Spectral and kinetic studies on the formation of eosinophil peroxidase compound I and its reaction with halides and thiocyanate Biochemistry. 2000 Dec 19;39(50):15578-84._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/20974700">10: Reszka KJ, Sallans L, Macha S, Brown K, McGraw DW, Kovacic MB, Britigan BE. Airway peroxidases catalyze nitration of the {beta}2-agonist salbutamol and decrease its pharmacological activity J Pharmacol Exp Ther. 2011 Feb;336(2):440-9. </a>_x000D_ _x000D_ <strong>Products Related to Eosinophil Peroxidase (Native Human) can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>