BMS-1
BMS-1 is an inhibitor of the PD-1/PD-L1 protein/protein interaction (IC50 between 6 and 100 nM) [1][2].
Product Specifications
CAS Number
[1675201-83-8]
Product Name Alternative
PD-1/PD-L1 inhibitor 1
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; PD-1/PD-L1
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/PD1-PDL1-inhibitor-1.html
Concentration
10mM
Purity
99.71
Solubility
DMF : 5 mg/mL (ultrasonic) |DMSO : 7.14 mg/mL (ultrasonic) |Methanol : 25 mg/mL (ultrasonic)
Smiles
O=C([C@H]1N(CC2=C(OC)C=C(OCC3=C(C)C(C4=CC=CC=C4)=CC=C3)C=C2OC)CCCC1)O
Molecular Formula
C29H33NO5
Molecular Weight
475.58
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-19991/BMS-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-19991/BMS-1-SDS-MedChemExpress.pdf
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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