Myostatin inhibitory peptide 7 (TFA)

Myostatin inhibitory peptide 7 TFA is a 23 amino acids peptide, which is derived from amino acids 21 to 43 of the mouse myostatin prodomain. Myostatin inhibitory peptide 7 TFA inhibits myostatin with a Kd of 29.7 nM. Myostatin inhibitory peptide 7 TFA can be used for researches of muscle atrophic disorders[1].

Product Specifications

UNSPSC

12352209

Target

TGF-beta/Smad

Type

Peptides

Related Pathways

Stem Cell/Wnt; TGF-beta/Smad

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/myostatin-inhibitory-peptide-7-tfa.html

Smiles

O=C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(N)=O)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H](CO)C(N[C@@H](CCCNC(N)=N)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCC(O)=O)C(N[C@@H](C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCCCN)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCC(N)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(C)C)C(N[C@@H](CO)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC2=CNC3=CC=CC=C23)N.OC(C(F)(F)F)=O.[x]

Molecular Formula

C130H222N42O32.xC2HF3O2

Molecular Weight

2885.42 (free base)

References & Citations

[1]Takayama K, et al., Identification of the minimum peptide from mouse myostatin prodomain for human myostatin inhibition. J Med Chem. 2015 Feb 12;58 (3) :1544-9.