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Maleuric acid

Maleuric acid has cytotoxicity on Ehrlich ascites tumor cells by preventing the entry of preprophase cells into mitosis[1].

Product Specifications

CAS Number

[105-61-3]

Product Name Alternative

N-carbamylmaleamic acid

UNSPSC

12352211

Hazard Statement

H302, H315, H318, H335

Target

DNA/RNA Synthesis; Mitosis

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/maleuric-acid.html

Purity

95.0

Solubility

DMSO : 116.67 mg/mL (ultrasonic)

Smiles

OC(/C=C\C(NC(N)=O)=O)=O

Molecular Formula

C5H6N2O4

Molecular Weight

158.11

Precautions

H302, H315, H318, H335

References & Citations

[1]T A OKADA, et al. Cytotoxic effects of maleuric acid and the structurally related compounds on Ehrlich ascites tumor cells. Cancer Res. 1963.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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