Maleuric acid
Maleuric acid has cytotoxicity on Ehrlich ascites tumor cells by preventing the entry of preprophase cells into mitosis[1].
Product Specifications
CAS Number
105-61-3
Product Name Alternative
N-carbamylmaleamic acid
UNSPSC
12352211
Hazard Statement
H302, H315, H318, H335
Target
DNA/RNA Synthesis; Mitosis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/maleuric-acid.html
Purity
95.0
Solubility
DMSO : 116.67 mg/mL (ultrasonic)
Smiles
OC(/C=C\C(NC(N)=O)=O)=O
Molecular Formula
C5H6N2O4
Molecular Weight
158.11
Precautions
H302, H315, H318, H335
References & Citations
[1]T A OKADA, et al. Cytotoxic effects of maleuric acid and the structurally related compounds on Ehrlich ascites tumor cells. Cancer Res. 1963.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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