What is the catalog number for 3-Deazaadenosine?

The catalog number for 3-Deazaadenosine is HY-W013332.

What sizes are available for 3-Deazaadenosine?

3-Deazaadenosine is available in the following size(s): 1 mg, 5 mg, 10 mg.

How many pack sizes does 3-Deazaadenosine come in?

3-Deazaadenosine is available in 3 different pack sizes.

Is 3-Deazaadenosine in stock?

3-Deazaadenosine is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures 3-Deazaadenosine?

3-Deazaadenosine is manufactured by QuantiMol.

What is the estimated delivery time for 3-Deazaadenosine?

Estimated delivery time for 3-Deazaadenosine is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for 3-Deazaadenosine?

The safety data sheet for 3-Deazaadenosine is available here: http://file.medchemexpress.com/batch_PDF/HY-W013332/3-Deazaadenosine-SDS-MedChemExpress.pdf.

3-Deazaadenosine

3-Deazaadenosine is an inhibitor of S-adenosylhomocysteine hydrolase, with a Ki of 3.9 μM; 3-Deazaadenosine has anti-inflammatory, anti-proliferative and anti-HIV activity.

Product Specifications

CAS Number

6736-58-9

UNSPSC

12352005

Hazard Statement

H302, H312, H315, H319, H331, H335

Target

HIV; S-adenosylhomocysteine hydrolase (SAHH)

Type

Reference compound

Related Pathways

Anti-infection; Epigenetics; Metabolic Enzyme/Protease

Applications

COVID-19-anti-virus

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/3-Deazaadenosine.html

Purity

99.87

Solubility

DMSO : 130 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

Smiles

O[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C3=C(C(N)=NC=C3)N=C2

Molecular Formula

C11H14N4O4

Molecular Weight

266.26

Precautions

H302, H312, H315, H319, H331, H335

References & Citations

[1]Gordon RK, et al. Anti-HIV-1 activity of 3-deaza-adenosine analogs. Inhibition of S-adenosylhomocysteine hydrolase and nucleotide congeners. Eur J Biochem. 2003 Sep;270 (17) :3507-17.|[2]Jeong SY, et al. 3-deazaadenosine, a S-adenosylhomocysteine hydrolase inhibitor, has dual effects on NF-kappaB regulation. Inhibition of NF-kappaB transcriptional activity and promotion of IkappaBalpha degradation. J Biol Chem. 1999 Jul 2;274 (27) :18981-8.|[3]Sedding DG, et al. 3-Deazaadenosine prevents smooth muscle cell proliferation and neointima formation by interfering with Ras signaling. Circ Res. 2009 May 22;104 (10) :1192-200.