16,16-Dimethylprostaglandin E1

16,16-Dimethylprostaglandin E1 (16,16-dimethyl-PGE1) is a PGE1 (HY-B0131) analog, induces bronchoconstrict and vascular smooth muscle contractions and suppresses the indomethacin induced cellular elongation[1][2][3].

Product Specifications

CAS Number

[41692-15-3]

Product Name Alternative

16,16-dimethyl-PGE1

UNSPSC

12352211

Hazard Statement

H225-H319-H336

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/16-16-dimethylprostaglandin-e1.html

Solubility

10 mM in DMSO

Smiles

CCCCC(C)(C)[C@H](O)/C=C/[C@@H]1[C@H](C(C[C@H]1O)=O)CCCCCCC(O)=O

Molecular Formula

C22H38O5

Molecular Weight

382.53

Precautions

P210-P233-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P370+P378-P403+P233-P403+P235-P405-P501

References & Citations

[1]Feuerstein G, et al., Prostaglandins, catecholamines, and cardiovascular responses to hemorrhage. Am J Physiol. 1981 Mar;240 (3) :R166-74.|[2]Jumblatt MM, et al., Prostaglandin E2 effects on corneal endothelial cyclic adenosine monophosphate synthesis and cell shape are mediated by a receptor of the EP2 subtype. Invest Ophthalmol Vis Sci. 1991 Feb;32 (2) :360-5.|[3]Strandberg K, et al., Bronchial effects of some prostaglandin E and F analogues. Acta Physiol Scand. 1977 Jun;100 (2) :172-81.