OXA-06
OXA-06 is a pharmacologic inhibitor of ROCK, possessing antitumor activity by impairing cell migration and MYPT1 phosphorylation in PANC-1 cells.
Product Specifications
CAS Number
[944955-32-2]
UNSPSC
12352005
Target
ROCK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton; Stem Cell/Wnt; TGF-beta/Smad
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/oxa-06.html
Smiles
FC1=C(CNCC2=CC=C(C3=C4C=CNC4=NC=C3)C=C2)C=CC=C1
Molecular Formula
C21H18FN3
Molecular Weight
331.39
References & Citations
[1]ROCK1 and ROCK2 are required for non-small cell lung cancer anchorage-independent growth and invasion
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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