NH2-Gly-PAB-Exatecan-D-glucuronic acid
NH2-Gly-PAB-Exatecan-D-glucuronic acid (Compound 8) is an intermediate, which reacts with NHS group to form drug-linker conjugate for ADC, Mal-Gly-PAB-Exatecan-D-glucuronic acid.
Product Specifications
CAS Number
2763252-31-7
UNSPSC
12352005
Target
ADC Payload
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/nh2-gly-pab-exatecan-d-glucuronic-acid.html
Smiles
NCC(NC(C=C1COC(N[C@@H]2C3=C4C(C(N5C4)=CC([C@](O)(C(OC6)=O)CC)=C6C5=O)=NC7=CC(F)=C(C)C(CC2)=C73)=O)=C(C=C1)O[C@@H]8O[C@@H]([C@H]([C@@H]([C@H]8O)O)O)C(O)=O)=O
Molecular Formula
C40H40FN5O14
Molecular Weight
833.77
References & Citations
[1]DICKGIESSER S, et al., Methods and tools for conjugation to antibodies. WO2023170239.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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