Canine IL-3 R alpha / CD123 Protein, His Tag
Canine IL-3 R alpha, His Tag (ILA-C52H3) is expressed from human 293 cells (HEK293) . It contains AA Ser 33 - Asp 315 (Accession # XP_038305195.1) .
Product Specifications
Background
Interleukin 3 receptor alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123) is a 70-kD glycoprotein member of the hematopoietin receptor superfamily. This protein associates with a beta subunit common to the receptors for IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF) to form a high-affinity receptor for IL-3. The interleukin-3 receptor α chain (CD123) has been identified as a potential immunotherapeutic target because it is overexpressed in AML compared with normal hematopoietic stem cells.
Specifications
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 34.9 kDa. The protein migrates as 45-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
XP_038305195.1
Expression Region
Ser 33 - Asp 315
Host
HEK293
Target
IL-3 R alpha
Conjugation
Unconjugated
Tag
C-10xHis
Source
Canine
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
90%
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
34.9 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
1mg*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/ILA-C52H3.pdf
Species
Canine
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