Harmane-d1
Harmane-d is the deuterium labeled Harmane. Harmane, a β-Carboline alkaloid (BCA), is a potent neurotoxin that causes severe action tremors and psychiatric manifestations. Harmane shows 1000-fold selectivity for I1-Imidazoline receptor (IC50=30 nM) over α2-adrenoceptor (IC50=18 μM) . Harmane is also a potent and selective inhibitor of monoamine oxidase (MAO) (IC50s=0.5 and 5 μM for human MAO A/B, respectively) [1][2][3][4].
Product Specifications
UNSPSC
12352005
Target
Adrenergic Receptor; Imidazoline Receptor; Monoamine Oxidase
Type
Isotope-Labeled Compounds
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer; Neurological Disease
Purity
98.01
Solubility
DMSO : 50mg/mL (ultrasonic)
Smiles
CC1=NC([2H])=CC2=C1NC3=C2C=CC=C3
Molecular Formula
C12H9DN2
Molecular Weight
183.23
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
