Harmane-d1
Harmane-d is the deuterium labeled Harmane. Harmane, a β-Carboline alkaloid (BCA), is a potent neurotoxin that causes severe action tremors and psychiatric manifestations. Harmane shows 1000-fold selectivity for I1-Imidazoline receptor (IC50=30 nM) over α2-adrenoceptor (IC50=18 μM) . Harmane is also a potent and selective inhibitor of monoamine oxidase (MAO) (IC50s=0.5 and 5 μM for human MAO A/B, respectively) [1][2][3][4].
Product Specifications
UNSPSC
12352005
Target
Adrenergic Receptor; Imidazoline Receptor; Monoamine Oxidase
Type
Isotope-Labeled Compounds
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer; Neurological Disease
Purity
98.01
Solubility
DMSO : 50mg/mL (ultrasonic)
Smiles
CC1=NC([2H])=CC2=C1NC3=C2C=CC=C3
Molecular Formula
C12H9DN2
Molecular Weight
183.23
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
CD56 (CD56 Antigen, Cell Adhesion Molecule Neural 1, MSK39, Neural Cell Adhesion Molecule 1, NCAM 1, NCAM1, NCAM 120, NCAM 140, NCAM 180) (MaxLight 550)
Lentiviral human MFAP5 shRNA (UAS) - Lentiviral human MFAP5 shRNA (UAS) (25)