Tyk2-IN-18-d3
Tyk2-IN-18-d3 (Compound 18) is a Tyk2 inhibitor with an IC50 value of IL-23 and IFNα. Tyk2-IN-18-d3 can be used for research on autoimmune diseases[1].
Product Specifications
CAS Number
[3018160-68-1]
UNSPSC
12352005
Target
IFNAR; Interleukin Related; JAK
Type
Isotope-Labeled Compounds
Related Pathways
Epigenetics; Immunology/Inflammation; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Solubility
10 mM in DMSO
Smiles
C[C@@H]1C(C(C2=CC=NC(NC3=CC(NC(C4CC4)=O)=NC=C3C(CC([2H])([2H])[2H])=O)=C2N1C)=N5)=NN5C
Molecular Formula
C23H23D3N8O2
Molecular Weight
449.52
References & Citations
[1]Anjali Pandey, et al. Tyk2 inhibitors and uses thereof. WIPO (PCT) . WO2023227946A1. 2023-11-30
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Curated Selection
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