Human Monocyte-Derived Dendritic Cells

Human Monocyte-Derived Dendritic Cells provide an ideal culture model for the study of the initiation of immune responses, delivery of antigens to dendritic cells, cytokine production, vaccines and Toll-like receptors (TLRs). Dendritic Cells are derived from monocytes that have been cultured with IL-4 and GM-CSF. Our Dendritic Cells are quality tested via flow cytometry to ensure proper expression of dendritic markers. Dendritic cells express CD11c and HLA-DR. The expression of CD3 (T cells), CD19 (B cells), CD14 (monocytes/macrophages), and CD80 (a maturation marker) is also analyzed to ensure depletion of these cell types. Cell Features: Dendritic Cells are derived from monocytes cultured with interleukin 4 and granulocyte-monocyte colony stimulating factor. Dendritic Cells are extensively tested for quality and optimal performance. AcceGen guarantees performance and quality.