Human Brain Vascular Smooth Muscle Cells

Vascular smooth muscle cell is the cellular substate of most significant arterial disease. The increased growth potential of vascular smooth muscle cells represents one of the crucial anomalies responsible for the development of essential vascular diseases. New studies demonstrate that vascular smooth muscle cells express ICAM-1 and VCAM-1, which may contribute to the inflammatory reaction in the vascular wall and may actively be involved in the progression and stability of vascular disease. In vitro culture of human VSMC as a model of vascular research played a critical role and continues providing information in the pharmacology and the therapy of vascular diseases.HBVSMC from AcceGen Research Laboratories are isolated from human brain. HBVSMC are cryopreserved at secondary culture after purification and delivered frozen. Each vial contains >5×10^5 cells in 1 ml volume. HBVSMC are characterized by immunofluorescent method with antibodies to Α-smooth muscle actin and desmin. HBVSMC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HBVSMC are guaranteed to further expand for 15 population doublings in the condition provided by AcceGen Research Laboratories.