2-Methoxyhydroquinone

2-Methoxyhydroquinone is a phenolic compound that reduces TNF-α-induced production of chemokine (C-C motif) ligand 2 (CCL2) with an IC50 value of 64.3 µM. 2-Methoxyhydroquinone is also a precursor in the synthesis of the Hsp90 inhibitor Geldanamycin (HY-15230) [1][2].

Product Specifications

CAS Number

[824-46-4]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

HSP

Type

Natural Products

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/2-methoxyhydroquinone.html

Purity

99.57

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

COC1=C(O)C=CC(O)=C1

Molecular Formula

C7H8O3

Molecular Weight

140.14

Precautions

H302, H315, H319, H335

References & Citations

[1]Houser KR, et al. Anti-inflammatory effects of methoxyphenolic compounds on human airway cells. J Inflamm (Lond) . 2012 Mar 13;9:6.|[2]Qin HL, et al. Total synthesis of the Hsp90 inhibitor geldanamycin. Org Lett. 2008 Jun 19;10 (12) :2477-9.