3-OH-Kynurenamine (dihydroiodide)
3-OH-Kynurenamine dihydroiodide is the dihydroiodide form of 3-OH-Kynurenamine (HY-156908) . 3-OH-Kynurenamine dihydroiodide is an activator for aryl hydrocarbon receptor (AhR), and thus regulates the immune response. 3-OH-Kynurenamine dihydroiodide upregulates the expressions of Ido1 and Tgfb1, ameliorates the skin inflammation in psoriasis mouse model and kidney damage in nephrotoxic lupus mouse model[1].
Product Specifications
CAS Number
[2155855-77-7]
UNSPSC
12352005
Hazard Statement
H302, H312, H315, H319, H332, H335
Target
Aryl Hydrocarbon Receptor
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/3-oh-kynurenamine-dihydroiodide.html
Purity
99.56
Solubility
DMSO : 20.83 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=CC(O)=C1N)CCN.[H]I.[H]I
Molecular Formula
C9H14I2N2O2
Molecular Weight
436.03
Precautions
H302, H312, H315, H319, H332, H335
References & Citations
[1]Laura SANTAMBROGIO. Immunoregulatory role of 3-oh-kynurenamine and uses thereof. Patent, WO2019178013A1.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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