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2-Ethynyl-adenosine

2-Ethynyl-labeled adenosine (2-EA) can be used to measure de novo mRNA poly(A) tail synthesis in proliferating cells. 2-EA is cell permeable and incorporates into nascent mRNA transcripts both transcriptionally by RNA polymerase I,II and III and posttranscriptionally by poly(A) polymerase instead of their natural analolg adenosine.

Product Specifications

UNSPSC

12352208

UNSPSC Description

Nucleic acids

HS Code

29349990

eClass Number

34160990

eClass Product Group

Nucleinsäure (nicht klassifiziert)

Applications

mRNA poly(A) tail synthesis monitoring[1]

Purity

≥ 95 % (HPLC)

Form

Solid

Color

White to off-White

Autoclavability

false

Solubility

up to 4.0 mM in 1 x PBS

Smiles

C12c(nc(nc2n(cn1)[C@H]1[C@@H]([C@@H]([C@H](O1)CO)O)O)C#C)N

Shipping Conditions

Shipped at ambient temperature

Storage Conditions

Store at -20 °C. Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Storage Temperature

Store at -20 °C

Notes

Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Shelf Life

12 months after date of delivery

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