Posovolone

Posovolone (Co 134444) is an orally active, neuroactive steroid. Posovolone has anticonvulsant and anxiolytic-like activity as well as ataxic effects[1].

Product Specifications

CAS Number

[256955-84-7]

Product Name Alternative

Co 134444

UNSPSC

12352005

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/posovolone.html

Purity

99.98

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C([C@@]1([H])CC[C@@]2([H])[C@]3([H])CC[C@@]4([H])C[C@](COC)(O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C)CN5C=CN=C5

Molecular Formula

C26H40N2O3

Molecular Weight

428.61

References & Citations

[1]Vanover KE, et al. Behavioral characterization of Co 134444 (3alpha-hydroxy-21- (1'-imidazolyl) -3beta-methoxymethyl-5alpha- pregnan-20-one), a novel sedative-hypnotic neuroactive steroid. Psychopharmacology (Berl) . 2001;155 (3) :285-291.