Z-DEVD-CMK
Z-DEVD-CMK is an irreversible inhibitor of most of the cathepsins in vitro[1].
Product Specifications
CAS Number
250584-13-5
UNSPSC
12352209
Target
Cathepsin
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/z-devd-cmk.html
Purity
98.99
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC([C@H](NC([C@@H](NC([C@@H](NC(OCC1=CC=CC=C1)=O)CC(O)=O)=O)CCC(O)=O)=O)C(N[C@H](C(CCl)=O)CC(O)=O)=O)C
Molecular Formula
C27H35ClN4O12
Molecular Weight
643.04
References & Citations
[1]Rozman-Pungercar J, et al. Inhibition of papain-like cysteine proteases and legumain by caspase-specific inhibitors: when reaction mechanism is more important than specificity. Cell Death Differ. 2003 Aug;10 (8) :881-8.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
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