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Z-DEVD-CMK

Z-DEVD-CMK is an irreversible inhibitor of most of the cathepsins in vitro[1].

Product Specifications

CAS Number

[250584-13-5]

UNSPSC

12352209

Target

Cathepsin

Type

Peptides

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/z-devd-cmk.html

Purity

98.99

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC([C@H](NC([C@@H](NC([C@@H](NC(OCC1=CC=CC=C1)=O)CC(O)=O)=O)CCC(O)=O)=O)C(N[C@H](C(CCl)=O)CC(O)=O)=O)C

Molecular Formula

C27H35ClN4O12

Molecular Weight

643.04

References & Citations

[1]Rozman-Pungercar J, et al. Inhibition of papain-like cysteine proteases and legumain by caspase-specific inhibitors: when reaction mechanism is more important than specificity. Cell Death Differ. 2003 Aug;10 (8) :881-8.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Scientific Category

Peptides

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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