Anti Human PRAME Polyclonal
This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
Product Specifications
CAS Number
9007-83-4
Reactivity
Human
Immunogen
Recombinant Protein
Clonality
Polyclonal
Type
Antibodies-Polyclonal
Applications
WB,ELISA
Concentration
1ug/ul
Purity
Antigen Affinity Purified
Buffer
PBS, pH 7.4 with 0.1% sodium azide, 50% Glycerol
Shipping Conditions
Ice Pack
Storage Conditions
This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Fragment
IgG
Applications Notes
ELISA 1:1,000~100,000 Western blotting 1:100~1,000
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