Anti-MUC12 Antibody

Rabbit Polyclonal Antibody specific to MUC12

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

MUC-12, Mucin-11, MUC-11

Gene Name

MUC12

NCBI Gene ID

UniProt

Q9UKN1

Cellular Locus

Membrane, Single-pass type I membrane protein

Host

Rabbit

Reactivity

Human

Immunogen

Peptide corresponding to aa 10-24 of human Mucin 12.

Target Antigen

Mucin-12

Target

MUC12

Clonality

Polyclonal

Type

Antibody

Applications

Field of Research

Cancer research

Purification Method

Purified by peptide immuno-affinity chromatography

Concentration

Lot Specific

Dilution

Dilute in PBS or medium which is identical to that used in the assay system.

Format

Purified

Form

Liquid

Buffer

Phosphate Buffered Saline

Function

Involved in epithelial cell protection, adhesion modulation, and signaling. May be involved in epithelial cell growth regulation. Stimulated by both cytokine TNF-alpha and TGF-beta in intestinal epithelium. {PubMed:17058067}.

Additionnal Information

Immunoblotting: use at 1:500-1:1,000 dilution.

Storage Conditions

This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze- thaw cycles.

Specificity

This antibody recognizes human MUC12 (Mucin 12), a novel mucin that appears to be involved in epithelial cell growth regulation. MUC12 is down-regulated in colorectal cancers.