Anti-TGF beta1

TGFB is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. TGFB acts synergistically with TGFA (MIM 190170) in inducing transformation. It also acts as a negative autocrine growth factor. Dysregulation of TGFB activation and signaling may result in apoptosis. Many cells synthesize TGFB and almost all of them have specific receptors for this peptide. TGFB1, TGFB2 (MIM 190220), and TGFB3 (MIM 190230) all function through the same receptor signaling systems.[

Product Specifications

CAS Number

9007-83-4

Reactivity

Human,Mouse

Immunogen

partial recombinate protein

Clonality

Polyclonal

Type

Antibodies-Polyclonal

Applications

WB,IHC,ELISA

Concentration

100ug/100ul

Purity

Protein A purified

Buffer

PBS, pH 7.4 with 0.02% Sodium Azide

Shipping Conditions

Ice Pack

Storage Conditions

This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Specificity

TGF beta1 antibody detects endogenous levels of TGF1 beta1 protein. Not tested with other proteins

Applications Notes

Recommended dilutions Peptide ELISA: 1:80,000 WB: 1/200 - 1/1000 IHc:1/50-1/200 Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user