Anti-PPL

The protein encoded by this gene is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling processes, is reported to interact with this protein, suggesting a possible role for this protein as a localization signal in AKT1-mediated signaling. [provided by RefSeq, Jul 2008]

Product Specifications

CAS Number

9007-83-4

Reactivity

Human

Immunogen

Rabbit polyclonal PPL (1) antibody was raised against a recombinate human PPL protein 775-868aa (BC114620).

Clonality

Polyclonal

Type

Antibodies-Polyclonal

Applications

WB,ELISA

Concentration

100ug/100ul

Purity

Affinity purified

Buffer

PBS, pH 7.4 with 0.02% sodium azide.

Shipping Conditions

Ice Pack

Storage Conditions

This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.