Imisopasem manganese
Imisopasem manganese (M40403) is a stable non-peptidyl mimetic of manganese superoxide MnSOD.
Product Specifications
CAS Number
218791-21-0
Product Name Alternative
M40403; GC4403
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
SOD
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Imisopasem-manganese.html
Purity
98.15
Solubility
H2O : 25 mg/mL (ultrasonic)
Smiles
[Cl-][Mn+2]1234([Cl-])[N]5=C6C=CC=C5CN1[C@]7([H])CCCC[C@@]7([H])N2CCN3[C@@](CCCC8)([H])[C@]8([H])N4C6
Molecular Formula
C21H31Cl2MnN5
Molecular Weight
479.35
Precautions
H302, H315, H319, H335
References & Citations
[1]Salvemini D, et al. Pharmacological manipulation of the inflammatory cascade by the superoxide dismutase mimetic, M40403. Br J Pharmacol. 2001 Feb;132 (4) :815-27.|[2]Masini E, et al. Protective effects of M40403, a selective superoxide dismutase mimetic, in myocardial ischaemia and reperfusion injury in vivo. Br J Pharmacol. 2002 Jul;136 (6) :905-17.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
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