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Imisopasem manganese

Imisopasem manganese (M40403) is a stable non-peptidyl mimetic of manganese superoxide MnSOD.

Product Specifications

CAS Number

[218791-21-0]

Product Name Alternative

M40403; GC4403

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

SOD

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Imisopasem-manganese.html

Purity

98.15

Solubility

H2O : 25 mg/mL (ultrasonic)

Smiles

[Cl-][Mn+2]1234([Cl-])[N]5=C6C=CC=C5CN1[C@]7([H])CCCC[C@@]7([H])N2CCN3[C@@](CCCC8)([H])[C@]8([H])N4C6

Molecular Formula

C21H31Cl2MnN5

Molecular Weight

479.35

Precautions

H302, H315, H319, H335

References & Citations

[1]Salvemini D, et al. Pharmacological manipulation of the inflammatory cascade by the superoxide dismutase mimetic, M40403. Br J Pharmacol. 2001 Feb;132 (4) :815-27.|[2]Masini E, et al. Protective effects of M40403, a selective superoxide dismutase mimetic, in myocardial ischaemia and reperfusion injury in vivo. Br J Pharmacol. 2002 Jul;136 (6) :905-17.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 2

Available Sizes

Curated Selection

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