Anti-PEA15
This gene encodes a death effector domain-containing protein, which is a major phosphoprotein in astrocytes, and an endogenous substrate for protein kinase C. Studies using knockout mice suggest that this protein may protect astrocytes from TNF-induced apoptosis. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. [provided by RefSeq, Sep 2011]
Product Specifications
CAS Number
9007-83-4
Reactivity
Human,Mouse
Immunogen
Rabbit polyclonal PEA15 antibody was raised against a 16 amino acid peptide from near the C terminal residues of human PEA15 protein
Clonality
Polyclonal
Type
Antibodies-Polyclonal
Applications
IHC,ELISA
Concentration
100ug/100ul
Purity
Affinity purified
Buffer
PBS, pH 7.4 with 0.02% Sodium Azide
Shipping Conditions
Ice Pack
Storage Conditions
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Fragment
IgG
Specificity
The peptide sequence of this antibody is corresponding to amino acids of human 80-130aa，This antibody is predicted to recognize mouse PEA15 protein because of synthesized peptide amino acid 100% homology with mouse PEA15 protein.
Applications Notes
For research use only
Peptide ELISA titer: 1:10,000-1:40,000
Immunohistochemistry: 1:200-500
Optimal dilutions/concentrations should be determined by the end use
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