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Anti-PDK1

Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2013]

Product Specifications

Reactivity

Human

Immunogen

Rabbit polyclonal pdk1 antibody was raised against a 16 amino acid peptide from near the C terminal residues of human pdk1 protein.

Clonality

Polyclonal

Type

Antibodies-Polyclonal

Applications

IHC,ELISA

Concentration

100ug/100ul

Purity

Affinity purified

Buffer

PBS, pH 7.4 with 0.02% Sodium Azide

Shipping Conditions

Ice Pack

Storage Conditions

This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Fragment

IgG

Applications Notes

Peptide ELISA titer: 1:5,000-1:20,000 Immunohistochemistry: 1:100-500 Optimal dilutions/concentrations should be determined by the end use.

CAS Number

9007-83-4

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