Anti-PAWR

The tumor suppressor WT1 represses and activates transcription. Anti-Prostate Apoptosis Response Protein Par-4 (PAWR) is a WT1-interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc finger DNA binding domain of WT1. This protein is specifically upregulated during apoptosis of prostate cells

Product Specifications

CAS Number

9007-83-4

Reactivity

Human

Immunogen

Synthetic peptide conjugated to KLH

Clonality

Polyclonal

Type

Antibodies-Polyclonal

Applications

WB,ELISA

Concentration

100ug/100ul

Purity

Protein A purified

Buffer

PBS, pH 7.4 with 0.02% Sodium Azide

Shipping Conditions

Ice Pack

Storage Conditions

This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Fragment

Rabbit IgG

Specificity

PAWR antibody detects endogenous levels of PAWR protein. Not tested with other proteins

Applications Notes

Recommended dilutions Peptide ELISA: 1:20,000 WB: 1/100 - 1/500 Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user