Anti-EZH2
Enhancer of zeste homolog 2, or EZH2, is encoded by the EZH2 gene. EZH2 helps control transcriptional repression of genes that regulate cell differentiation. This makes the gene a usual target for anti-cancer therapy because it is usually involved in cancer cell proliferation. EZH2 is a gene suppressor so many tumor suppressor genes that are normally turned on are turned off when it becomes overexpressed. Other diseases related to this gene are Weaver syndrome and Ezh2-related overgrowth. EZH2 is useful in the field of cancer research particularly in developing different methods of anti-cancer therapy.
Product Specifications
CAS Number
9007-83-4
Reactivity
Human
Immunogen
Recombinant peptide within Human EZH2
Clonality
Monoclonal
Type
Antibodies-Monoclonal
Applications
WB,IP
Concentration
100µg/100µl
Purity
The antibody was affinity-purified from hybridoma supernatant by affinity-chromatography.
Buffer
PBS, pH 7.4 with 0.05% sodium azide
Shipping Conditions
Ice Pack
Storage Conditions
Fragment
IgG2a
Specificity
Human EZH2
Applications Notes
WB: 1:500~1:2500; IP: Use at 2-10 µg/mg of lysate. Optimal dilutions should be calculated by the end user based on their specific application.
Frequently Asked Questions
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