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Anti-CTLA-4

Encoded by the CTLA4 gene, Cytotoxic T-Lymphocyte Antigen 4 (CTLA-4), also known as CD152, is a protein that functions in immune system regulation. It is expressed on the surface of helper T cells and transmits and inhibitory signal to T cells. Diseases associated with the CTLA4 gene include various autoimmune diseases, such as systemic lupus erythematosus, and insulin-dependent diabetes mellitus.

Product Specifications

CAS Number

9007-83-4

Reactivity

Human

Immunogen

Spleen cells fused with Sp2/0-Ag14 cells

Clonality

Monoclonal

Type

Antibodies-Monoclonal

Applications

ELISA

Concentration

100µg/100µl

Purity

The antibody was affinity-purified from hybridoma supernatant by affinity-chromatography.

Buffer

PBS, pH 7.4 with 0.05% sodium azide

Shipping Conditions

Ice Pack

Storage Conditions

This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Fragment

IgG2a kappa

Specificity

Human CTLA-4/CD152.

Applications Notes

Use at an assay dependent concentration.

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