Anti-CD2
CD2 is found as a surface antigen found on all peripheral blood T-cells and the majority of NK cells. It interacts with lymphocyte function-associated antigen (LFA-3/CD58) on antigen presenting cells to optimize immune recognition or CD48/BCM1 in rodents to mediate adhesion between T-cells and other cell types. CD2 also acts as a co-stimulatory molecule on T and NK cells and its cytoplasmic domain is implicated in the signaling function. As a specific marker for T and NK cells which is also expressed by the great majority of T cell lymphomas and leukaemias, CD2 can be used to distinguish these conditions from B cell neoplasms.
Product Specifications
CAS Number
9007-83-4
Reactivity
Human
Immunogen
Human cytolytic T lymphocytes
Clonality
Monoclonal
Type
Antibodies-Monoclonal
Applications
WB,ELISA
Concentration
100µg/100µl
Purity
The antibody was affinity-purified from hybridoma supernatant by affinity-chromatography.
Buffer
PBS, pH 7.4 with 0.05% sodium azide
Shipping Conditions
Ice Pack
Storage Conditions
Fragment
IgG1
Specificity
Human CD2
Applications Notes
WB and ELISA: 1:500~1:1000. Optimal dilutions should be calculated by the end user based on their specific application.
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