Anti-Caspase 7

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase 3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms.

Product Specifications

Reactivity

Human,Mouse,Rat

Immunogen

Synthetic peptide conjugated to KLH

Clonality

Polyclonal

Type

Antibodies-Polyclonal

Applications

IHC,ELISA

Concentration

100ug/100ul

Purity

Affinity purified

Buffer

PBS, pH 7.4 with 0.02% Sodium Azide

Shipping Conditions

Ice Pack

Storage Conditions

This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Specificity

Not yet tested in other species.

Applications Notes

For research use only Peptide ELISA titer: 1:20,000-1:80,000 Immunohistochemistry: 1:50-200 Optimal dilutions/concentrations should be determined by the end use