Anti-APBA1

The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. [provided by RefSeq, Jul 2008]

Product Specifications

Reactivity

Human

Immunogen

Rabbit polyclonal APBA1 antibody was raised against a 14 amino acid peptide from the intermediate residues of human APBA1.

Clonality

Polyclonal

Type

Antibodies-Polyclonal

Applications

IHC,ELISA

Concentration

100ug/100ul

Purity

Affinity purified

Buffer

PBS, pH 7.4 with 0.02% Sodium Azide

Shipping Conditions

Ice Pack

Storage Conditions

This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Fragment

IgG

Applications Notes

For research use only Peptide ELISA titer: 1:5,000-1:20,000 Immunohistochemistry: 1:100-500 Optimal dilutions/concentrations should be determined by the end use