Anti-APBA1

The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adaptor protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilises APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion.

Product Specifications

CAS Number

9007-83-4

Reactivity

Human,Mouse

Immunogen

Synthetic peptide conjugated to KLH

Clonality

Polyclonal

Type

Antibodies-Polyclonal

Applications

WB,ELISA

Concentration

100ug/100ul

Purity

Protein A purified

Buffer

PBS, pH 7.4 with 0.02% Sodium Azide

Shipping Conditions

Ice Pack

Storage Conditions

This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Fragment

Rabbit IgG

Specificity

APBA1 antibody detects endogenous levels of APBA1 protein. Not tested with other proteins

Applications Notes

Recommended dilutions Peptide ELISA: 1:20,000 WB: 1/200 - 1/1000 Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user