Anti-AGRN

This gene encodes one of several proteins that are critical in the development of the neuromuscular junction (NMJ), as identified in mouse knock-out studies. The encoded protein contains several laminin G, Kazal type serine protease inhibitor, and epidermal growth factor domains. Additional post-translational modifications occur to add glycosaminoglycans and disulfide bonds. In one family with congenital myasthenic syndrome affecting limb-girdle muscles, a mutation in this gene was found. [provided by RefSeq, Aug 2011]

Product Specifications

Reactivity

Human,Mouse,Rat

Immunogen

Rabbit polyclonal AGRN antibody was raised against a peptide from N terminal residues of human AGRN protein.

Clonality

Polyclonal

Type

Antibodies-Polyclonal

Applications

IHC,ELISA

Concentration

100ug/100ul

Purity

Affinity purified

Buffer

PBS, pH 7.4 with 0.02% Sodium Azide

Shipping Conditions

Ice Pack

Storage Conditions

This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Fragment

IgG

Applications Notes

For research use only Peptide ELISA titer: 1:10,000-1:40,000 Immunohistochemistry: 1:100-500 Optimal dilutions/concentrations should be determined by the end use.

CAS Number

9007-83-4

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