Anti-ADD1

Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2 )/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.

Product Specifications

CAS Number

9007-83-4

Reactivity

Human

Immunogen

Synthetic peptide conjugated to KLH

Clonality

Polyclonal

Type

Antibodies-Polyclonal

Applications

WB,ELISA

Concentration

100ug/100ul

Purity

Protein A purified

Buffer

PBS, pH 7.4 with 0.02% Sodium Azide

Shipping Conditions

Ice Pack

Storage Conditions

This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Fragment

Rabbit IgG

Specificity

ADD1 antibody detects endogenous levels of total ADD1 protein. Not tested with other proteins

Applications Notes

Recommended dilutions Peptide ELISA: 1:16,000 IF: 1/50. WB: 1/500 - 1/1000. Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user