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Anti-TRPC6

The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2). [provided by RefSeq, Mar 2009]

Product Specifications

CAS Number

9007-83-4

Reactivity

Human,Mouse,Rat

Immunogen

The antibody was produced against a synthesized peptide Corresponding to the amino terminal sequence from mouse TRPC6 protein (-RRNESQDYLLMDELG-).

Clonality

Polyclonal

Type

Antibodies-Polyclonal

Applications

WB

Concentration

100ug/100ul

Purity

Affinity purified

Buffer

Rabbit IgG in phosphate buffered saline (without Mg<sup>2</sup>+ and Ca<sup>2</sup>+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Shipping Conditions

Ice Pack

Storage Conditions

This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Fragment

IgG

Specificity

TRPC6 antibody detects endogenous levels of total TRPC6 protein.

Applications Notes

WB: 1:500~1:1000

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