Anti-Smad3 (Ab-208)

The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis. [provided by RefSeq, Apr 2009]

Product Specifications

CAS Number

9007-83-4

Reactivity

Human,Mouse,Rat

Immunogen

The antibody was produced against synthesized non-phosphopeptide derived from human Smad3 around the phosphorylation site of serine 208 (N-L-SP-P-N).

Clonality

Polyclonal

Type

Antibodies-Polyclonal

Applications

IHC,IP

Concentration

100ug/100ul

Purity

Affinity purified

Buffer

Rabbit IgG in phosphate buffered saline (without Mg<sup>2</sup>+ and Ca<sup>2</sup>+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Shipping Conditions

Ice Pack

Storage Conditions

This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.