(E/Z) -Icerguastat (acetate)
(E/Z) -Icerguastat ((E/Z) -Sephin1) acetate is a selective inhibitor of the phosphatase regulatory subunit PPP1R15A (R15A) . (E/Z) -Icerguastat acetate can be used for protein misfolding diseases research[1].
Product Specifications
CAS Number
469866-31-7
Product Name Alternative
(E/Z) -Sephin1 (acetate) ; (E/Z) -IFB-088 (acetate)
UNSPSC
12352005
Target
Phosphatase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/e-z-icerguastat-acetate.html
Smiles
O=C(C)O.ClC1=C(/C=N/NC(N)=N)C=CC=C1
Molecular Formula
C10H13ClN4O2
Molecular Weight
256.69
References & Citations
[1]Das I, et al. Preventing proteostasis diseases by selective inhibition of a phosphatase regulatory subunit. Science. 2015 Apr 10;348 (6231) :239-42.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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