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(E/Z) -Icerguastat (acetate)

(E/Z) -Icerguastat ((E/Z) -Sephin1) acetate is a selective inhibitor of the phosphatase regulatory subunit PPP1R15A (R15A) . (E/Z) -Icerguastat acetate can be used for protein misfolding diseases research[1].

Product Specifications

CAS Number

469866-31-7

Product Name Alternative

(E/Z) -Sephin1 (acetate) ; (E/Z) -IFB-088 (acetate)

UNSPSC

12352005

Target

Phosphatase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/e-z-icerguastat-acetate.html

Smiles

O=C(C)O.ClC1=C(/C=N/NC(N)=N)C=CC=C1

Molecular Formula

C10H13ClN4O2

Molecular Weight

256.69

References & Citations

[1]Das I, et al. Preventing proteostasis diseases by selective inhibition of a phosphatase regulatory subunit. Science. 2015 Apr 10;348 (6231) :239-42.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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