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Anti-mTOR (Ab-2448)

The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq, Sep 2008]

Product Specifications

CAS Number

9007-83-4

Reactivity

Human,Mouse,Rat

Immunogen

The antibody was produced against synthesized non-phosphopeptide derived from human mTOR around the phosphorylation site of serine 2448 (T-D-SP-Y-S).

Clonality

Polyclonal

Type

Antibodies-Polyclonal

Applications

WB,IHC,IP

Concentration

100ug/100ul

Purity

Affinity purified

Buffer

Rabbit IgG in phosphate buffered saline (without Mg<sup>2</sup>+ and Ca<sup>2</sup>+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Shipping Conditions

Ice Pack

Storage Conditions

This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Fragment

IgG

Specificity

mTOR (Ab-2448) Antibody detects endogenous levels of total mTOR protein.

Applications Notes

WB: 1:500~1:1000 IHC: 1:50~1:100 IF:1:100~1:200

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